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Janumet (Sitagliptin phosphate + Metformin)

Anti Convulsants and Prescriptions » Diabetes » Janumet (Sitagliptin phosphate + Metformin)

Janumet (Sitagliptin Phosphate + Metformin) is used for treating type 2 diabetes in certain patients. It is used along with diet and exercise. Janumet works by increasing insulin release. It decreases the amount of sugar that the liver produces and the intestines absorb. It also helps to make your body more sensitive to the insulin that you naturally produce.

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About Janumet (Sitagliptin phosphate + Metformin):

Product Type: Diabetes

Brand name: Janumet. Generic name: Sitagliptin phosphate + Metformin. Janumet (Sitagliptin phosphate + Metformin) is used for: treating type 2 diabetes in certain patients. It is used along with diet and exercise. Janumet (Sitagliptin phosphate + Metformin) is a dipeptidyl peptidase-4 inhibitor and biguanide combination. It works by increasing insulin release. It decreases the amount of sugar that the liver produces and the intestines absorb. It also helps to make your body more sensitive to the insulin that you naturally produce. Do NOT use Janumet (Sitagliptin phosphate + Metformin) if: •you are allergic to any ingredient in Janumet (Sitagliptin phosphate + Metformin) •you have type 1 diabetes •you have congestive heart failure that is treated by medicine •you have a severe infection low blood oxygen levels kidney or liver problems or high blood ketone or acid levels (eg diabetic ketoacidosis) or you are severely dehydrated •you have had a stroke or a recent heart attack or you are in shock •you are 80 years old or older and have not had a kidney function test •you will be having surgery or certain lab procedures. Contact your doctor or health care provider right away if any of these apply to you. Before using Janumet (Sitagliptin phosphate + Metformin): Some medical conditions may interact with Janumet (Sitagliptin phosphate + Metformin). Tell your doctor or pharmacist if you have any medical conditions especially if any of the following apply to you: •if you are pregnant planning to become pregnant or are breast-feeding •if you are taking any prescription or nonprescription medicine herbal preparation or dietary supplement •if you have allergies to medicines foods or other substances •if you have a history of heart problems (eg heart failure) lung or breathing problems thyroid problems stomach or bowel problems (eg blockage paralysis) adrenal or pituitary problems or lactic acidosis •if you have a history of inflammation of the pancreas (pancreatitis) •if you have vomiting diarrhea poor health or nutrition low blood calcium or vitamin B12 levels or anemia or if you are dehydrated •if you have an infection fever recent injury or moderate to severe burns •if you drink alcohol or have a history of alcohol abuse •if you will be having surgery or certain lab procedures •if you take a beta-blocker (eg propranolol). Some MEDICINES MAY INTERACT with Janumet (Sitagliptin phosphate + Metformin). Tell your health care provider if you are taking any other medicines especially any of the following: •Amiloride cimetidine digoxin morphine procainamide quinidine quinine ranitidine triamterene trimethoprim or vancomycin because they may increase the risk of Janumet (Sitagliptin phosphate + Metformin)'s side effects •Calcium channel blockers (eg nifedipine) corticosteroids (eg prednisone) diuretics (eg furosemide hydrochlorothiazide) estrogen hormonal contraceptives (eg birth control pills) insulin isoniazid nicotinic acid phenothiazine (eg chlorpromazine) phenytoin sulfonylureas (eg glipizide) sympathomimetics (eg albuterol pseudoephedrine) or thyroid hormones (eg levothyroxine) because the risk of high or low blood sugar may be increased. This may not be a complete list of all interactions that may occur. Ask your health care provider if Janumet (Sitagliptin phosphate + Metformin) may interact with other medicines that you take. Check with your health care provider before you start stop or change the dose of any medicine. How to use Janumet (Sitagliptin phosphate + Metformin): Use Janumet (Sitagliptin phosphate + Metformin) as directed by your doctor. Check the label on the medicine for exact dosing instructions. •An extra patient leaflet is available with Janumet (Sitagliptin phosphate + Metformin). Talk to your pharmacist if you have questions about this information. •Take Janumet (Sitagliptin phosphate + Metformin) by mouth with food. •Take Janumet (Sitagliptin phosphate + Metformin) on a regular schedule to get the most benefit from it. Taking Janumet (Sitagliptin phosphate + Metformin) at the same times each day will help you remember to take it. •Continue to take Janumet (Sitagliptin phosphate + Metformin) even if you feel well. Do not miss any doses. •If you miss a dose of Janumet (Sitagliptin phosphate + Metformin) take it as soon as possible. If it is almost time for your next dose skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once. Ask your health care provider any questions you may have about how to use Janumet (Sitagliptin phosphate + Metformin). Important safety information: •Janumet (Sitagliptin phosphate + Metformin) may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Janumet (Sitagliptin phosphate + Metformin) with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it. •Follow the diet and exercise program given to you by your health care provider. •Do not drink large amounts of alcohol while you use Janumet (Sitagliptin phosphate + Metformin). Talk to your doctor or health care provider before you drink alcohol while you use Janumet (Sitagliptin phosphate + Metformin). •Do NOT take more than the recommended dose without checking with your doctor. •Be careful not to become dehydrated especially during hot weather or while you are being active. Dehydration may increase the risk of Janumet (Sitagliptin phosphate + Metformin)'s side effects. •Tell your doctor or dentist that you take Janumet (Sitagliptin phosphate + Metformin) before you receive any medical or dental care emergency care or surgery. •If vomiting or diarrhea occurs you will need to take care not to become dehydrated. Contact your doctor for instructions. •Carry an ID card at all times that says you have diabetes. Check your blood sugar levels as directed by your doctor. If they are often higher or lower than they should be and you take Janumet (Sitagliptin phosphate + Metformin) exactly as prescribed tell your doctor. •Janumet (Sitagliptin phosphate + Metformin) does not usually cause low blood sugar. Low blood sugar may be more likely to occur if you skip a meal exercise heavily or drink alcohol. It may also be more likely if you take Janumet (Sitagliptin phosphate + Metformin) along with certain medicines for diabetes (eg sulfonylureas insulin). It is a good idea to carry a reliable source of glucose (eg tablets gel) to treat low blood sugar. If this is not available you should eat or drink a quick source of sugar like table sugar honey candy orange juice or non-diet soda. This will raise your blood sugar level quickly. Tell your doctor right away if this happens. To prevent low blood sugar eat meals at the same time each day and do not skip meals. •Fever infection injury or surgery may increase your risk for high or low blood sugar levels. If any of these occur check your blood sugar closely and tell your doctor right away. •Janumet (Sitagliptin phosphate + Metformin) may commonly cause stomach upset indigestion nausea vomiting or diarrhea at the beginning of treatment. If you develop unusual or unexpected stomach problems or if you develop stomach problems later during treatment contact your doctor at once. This may be a sign of lactic acidosis.•Lab tests including kidney function liver function fasting blood glucose hemoglobin A1c and complete blood cell counts may be performed while you use Janumet (Sitagliptin phosphate + Metformin). These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments. •Use Janumet (Sitagliptin phosphate + Metformin) with caution in the ELDERLY; they may be more sensitive to its effects. Low blood sugar levels may also be more difficult to recognize in the elderly. •Janumet (Sitagliptin phosphate + Metformin) should be used with extreme caution in CHILDREN younger than 18 years old; safety and effectiveness in these children have not been confirmed. •PREGNANCY and BREAST-FEEDING: If you become pregnant contact your doctor. You will need to discuss the benefits and risks of using Janumet (Sitagliptin phosphate + Metformin) while you are pregnant. It is not known if Janumet (Sitagliptin phosphate + Metformin) is found in breast milk. If you are or will be breast-feeding while you use Janumet (Sitagliptin phosphate + Metformin) check with your doctor. Discuss any possible risks to your baby. When used for long periods of time Janumet (Sitagliptin phosphate + Metformin) may not work as well. If your blood sugar has been under control and then becomes hard to manage contact your doctor. Do not change the dose of your medicine without checking with your doctor. Possible side effects of Janumet (Sitagliptin phosphate + Metformin): All medicines may cause side effects but many people have no or minor side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome: •Diarrhea; gas; headache; indigestion; nausea; sore throat; stomach upset; stuffy or runny nose; vomiting; weakness. Seek medical attention right away if any of these SEVERE side effects occur: •Severe allergic reactions (rash; hives; itching; difficulty swallowing or breathing; tightness in the chest; swelling of the mouth face lips or tongue; unusual hoarseness); chest pain or discomfort; dizziness or lightheadedness; fast or difficult breathing; feeling of being unusually cold; fever chills or persistent sore throat; general feeling of being unwell; muscle pain or weakness; red blistered swollen or peeling skin; slow or irregular heartbeat; symptoms of pancreas inflammation (eg severe stomach or back pain with nausea or vomiting stomach tenderness or swelling fast heartbeat); unusual drowsiness; unusual or persistent stomach pain or discomfort; unusual tiredness or weakness. This is not a complete list of all side effects that may occur. If you have questions about side effects contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency please read the Guide to Reporting Problems to FDA. If OVERDOSE is suspected: Symptoms may include: •dizziness or lightheadedness; •fast or difficult breathing; •feeling of being unusually cold; •general feeling of being unwell; •muscle pain or tenderness; •slow or irregular heartbeat; •unusual drowsiness; •unusual stomach discomfort; •unusual weakness or tiredness. Proper storage of Janumet (Sitagliptin phosphate + Metformin): Store Janumet (Sitagliptin phosphate + Metformin) at room temperature between 68 and 77 degrees F (20 and 25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat moisture and light. Do not store in the bathroom. Keep Janumet (Sitagliptin phosphate + Metformin) out of the reach of children and away from pets.

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