Anti Convulsants and Prescriptions

Dilantin Infatabs Generic Phenytoin

Anti Convulsants and Prescriptions » Prescription Drugs 6 » Dilantin Infatabs Generic Phenytoin

Phenytoin is used to prevent and control seizures (also called an anticonvulsant or antiepileptic drug). It works by reducing the spread of seizure activity in the brain.Indication:Dilantin is indicated for the control of grand mal and psychomotor seizures. Dilantin will prevent or effectively decrease the incidence and severity of convulsive seizures in a high percentage of cases with patients exhibiting little tendency to become resistant to its action. Besides its effectiveness in controlling seizures Dilantin frequently improves the mental condition and outlook of epileptic patients and there is also increasing evidence that Dilantin is valuable in the prevention of seizures occurring during or after neurosurgery and in the treatment of certain cardiac arrythmias. Phenytoin serum level determinations may be necessary for optimal dosage adjustments (see Dosage and Administration).Dosage and Administration:Dilantin capsules (30 mg 100 mg) are formulated with the sodium salt of phenytoin.The free acid form of phenytoin is used in Dilantin Infatabs (50 mg) and Dilantin Paediatric Suspension (30 mg/5 mL).Because there is approximately an 8% increase in drug content with the free form over that of the sodium salt dosage adjustments and serum level monitoring may be necessary when switching from a product formulated with the free acid to a product formulated with the sodium salt and vice versa.GeneralDosage should be individualised to obtain maximum benefit. In some cases serum blood level determinations may be necessary for optimal dosage adjustments. Serum levels between 10 and 20 Бg/mL are considered to be clinically effective. With the recommended dosage a period of at least 7 to 10 days may be required to achieve therapeutic blood levels of Dilantin unless therapy is initiated with a loading dose. After the initial dose has been prescribed plasma levels should be determined and the dosage adjusted if necessary to obtain a level in the therapeutic range; 10 to 20 Бg/mL (40 to 80 Бmoles/L). Because phenytoin is hydroxylated in the liver by an enzyme system which is saturable at high plasma levels small incremental doses may increase the half-life and produce very substantial increases in serum levels when these are in the upper range.Oral AdministrationAlthough phenytoin has a relatively long plasma half-life thrice daily dosing may reduce the incidence of gastric irritation since lower doses can be administered with thrice daily dosing as compared with twice daily dosing. Recent studies suggest that a better correlation is achieved between plasma levels and dose by expressing the latter on a body-weight basis.AdultInitiate therapy with 4 to 5 mg/kg/day in 2 to 3 divided doses and assess plasma levels. A further upward dosage adjustment may be required to a maximum of 600 mg/day dosage increments should be made at about 2 week intervals. Plasma phenytoin levels should be monitored should higher doses be required.An initial dose of 6 to 7 mg/kg/day would be more likely to ensure therapeutic levels however there is a risk that such a dose may achieve levels exceeding 20 Бg/mL and increase the risk of toxicity.PaediatricInitiate therapy with 5 mg/kg/day in 2 to 3 equally divided doses not to exceed 300 mg daily. A recommended daily maintenance dosage is usually 4 to 8 mg/kg. Children over 6 years may require the minimum adult dose (300 mg/day).Paediatric dosage forms available include Dilantin Chewable Infatabs and Dilantin Paediatric Suspension.

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Dilantin Infatabs ( Generic Phenytoin )

Dilantin Infatabs (Generic Phenytoin)

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Anti Convulsants and Prescriptions: Dilantin Generic Phenytoin. Phenytoin is used to treat various types of convulsions and seizures. Phenytoin acts on the brain and nervous system in the treatment of epilepsy.Phenytoin comes as a capsule extended-release (long-acting) capsule chewable tablet and liquid to take by mouth. It usually is taken two or three times a day. However the extended-release capsules may be taken only once a day usually at bedtime. Follow the directions on your prescription label carefully and ask your doctor or pharmacist to explain any part you do not understand. Take phenytoin exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.Shake the liquid well before each use.Do not open crush or chew the extended-release capsules; swallow them whole.Continue to take phenytoin even if you feel well. Do not stop taking phenytoin without talking to your doctor especially if you have taken large doses for a long time. Abruptly stopping the drug can cause seizures. Your doctor probably will decrease your dose gradually. Buy Dilantin Generic Phenytoin and other Prescription Drugs 6 products online at Medstore. About Dilantin Generic Phenytoin: Product Type: Prescription Drugs 6 Dilantin ( Generic Phenytoin ) Dilantin (Generic Phenytoin) Generic Phenytoin 100mg 200 caps 30mg Generic Phenytoin Dilantin